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Thanks for getting back in touch with us, kama.
Yes, you can adjust the description column. I'd suggest following these steps.
You can check out this article for further guidance: Customise Invoices, Estimates and Sales Receipts.
As for the message box, this will appear on every invoice.
You can also attach files, and email sales forms to your customer within QuickBooks Online. This helps you personalise the invoices you sent.
Please get back to us if you need further assistance in managing your sales transactions. I'm always here to help.