Yes, there are two ways for this, @Janet32. 

You're on the right track in customizing the report to increase the font size.

First, you can memorize the report to save the current customization settings and print it directly. Here's how: 

1. Open your preferred report again. 
2. Customize it to increase the font size again. 
3. Select Memorize. 
4. Enter the Name like "Profit & Loss Detail (With Increased Font Size)."
5. Click OK. 

The screenshot below shows you the last three steps. 

The second option is to change your report default settings. 

1. Go to the Edit menu at the top. 
2. Select Preferences. 
3. Choose Reports & Graphs and click Company Preferences. 
4. Increase the font size under the Format button. 
5. Click OK. 

Once done, there are three ways to access the memorized report when printing it.

• Report Center
• Memorized Report List
• Reports menu

For more information, check out this article: Help Guide. 

Aside from memorizing the report, you can perform other tasks to help you efficiently manage your reporting needs for your business. These are the following: 

• Set Up And Modify Scheduled Reports
• Export Reports To Excel

Leave the comment below if you have follow-up concerns regarding reports or other inquiries. I'll gladly help. Keep safe.