Greetings, @avery3.

It'll depend on the type of report you're opening. For example, if you run the Sales by Customer Detail report, it'll show each line item from the invoice. Thus, it shows the Description of the line item on the Memo/Description column.

However, if you run the Transaction List by Customer report, it'll show each transaction without the details of the line items. Thus, it shows the message from the invoice as Memo/Description.

Furthermore, here's a great article you can check to learn more about running reports in QuickBooks Online (QBO): Run reports in QuickBooks Online.

Also, I'm adding this great resource that provides detailed information on how to generate reports that shows the data you need: Customize reports in QuickBooks Online.

Learning more about reports in your QBO account we'll ensure the accuracy of your accounts. Let me know if you have other concerns. I'm always here to help. Take care and have a good one!