I agree @Pwgmd and @srich ! This is happening on any computer. i believe its got to be a QBO account issue. Buggy programming etc. It happens on any computer i am using. I have tried 3 desktop computers at work and my laptop, as well as, my wifes... 5x Computers.. and... SAME ISSUE... 

When you click ANYTHING that "slides" open a window (on top of the open window?), it works the FIRST TIME ONLY. After that - I have to refresh my browser window in order for the item (invoice/estimate/etc) to open. Then, and this is the part that's actually REALLY frustrating. When you are done and close the invoice/estimate/etc, it goes back to the HOME SCREEN. Then I have to go back thru the menus to get the invoice/estimate/etc open again (Sales | Clients | (type name of client) | choose the invoice | (if its the wrong invoice... start from the BEGINNING AGAIN!)

ERRRR!!!!!!!

WAV