We are experiencing this issue with a brand new computer, new install of Office Home and Business 2019, and the latest version of Quickbooks Enterprise. 

We've tried the regedit fix, installs/reinstalls, user access control, modifying Excel options.... The recommended 'fixes' from Quickbooks - for two years(!) are time consuming and don't work. 

The copying and pasting of the forum administrators of the same 'fixes' are insulting.

I'm 100% certain there is a good developer at Intuit who could fix this. Why hasn't this happened? What a complete waste of time.