Hello dLearned!

Thank you for the screenshots. Let me assist you and explain the difference between memo and description.

The Memo field is used to add notes for the transaction as a whole, while the Description is for the line items. Based on your screenshots, you only added a memo but no description and the line item uses the COGS:Hotel and Travel Expenses account. It'll only reflect if you'll run Transaction Detail by Account or any report specific for American Express which is the payment account unless you'll also add it in the description.

Please check the screenshots I attached for your reference:

You can check this article if you need help in customizing or saving a report: Customize reports in QuickBooks Online.

Shoot a reply if you have other report-related concerns. Take care!