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You've been receiving bad advice from QB employees. @JaeAnnC's response of "The negative amount indicates that the balance has been paid and a refund was issued. You may leave it as is if your customer wants to apply this credit to future invoices." is contradictory and incorrect.
To answer your questions:
1) You don't need to create a credit memo first, you can just create a refund receipt. A credit memo is issued when the credit will be applied to a future invoice. A refund receipt is best when you want to issue a refund.
2) If you have -$100, then the customer has a $100 credit balance that can be applied to future invoices. Issuing a refund receipt does not create a negative balance. It doesn't affect the customer's A/R balance at all. So, if you are showing -$100, you issued a credit memo or some other entry that credited A/R $100. If you issued the $100 refund receipt, you can delete the entry causing the -$100 balance.