Thanks for joining this thread and for following the recommended troubleshooting steps provided above, @mdg3.

Since the issue persists after using the verify and rebuild tool, I recommend contacting our Customer Support Team. Currently, there's a specific issue for macOS Big Sur. 

As far as I want to call you, the QuickBooks Community has limited tools. They can further investigate the root cause of your issue and provide a fix.

If you can't get into your product, simply click Contact Us to reach us. For more info, feel free to view this resource: Contact QuickBooks Desktop support.

I've also included this link to guide you on how to fix data damage on your QuickBooks Desktop company file.

Don't hesitate to leave a comment below if you have other QuickBooks concerns. I'll get back to you as soon as I can. Keep safe always.