How can we apply your solution if quicbooks desktop will not even open?!?!
Two days ago, I closed a functional quickbooks program and when I tried to open it today, I get the attached error message. Once you click OK it shuts down and does not open. 
How on earth can the software coding be written in a way that requires and antiquated, obsolete program!?! 
Like many others, I have not used IE since the late 90's ... and I have owned this computer for 10 months and I have NEVER had IE enabled.
Possibly a Windows update removed it?! It is not in Windows Features, it is not in Programs...I do not have IE, only Microsoft Edge which is also never used. It is not on this computer. 
When calling Microsoft  Support we're told to contact QuickBooks ... but when contacting QuickBooks Support we're told this is a problem with Windows. However, if we want to pay for a Support Subscription they will happily assist. Yep...for real!! 
The title on the error message clearly states "QuickBooks has a problem". Well, that is the understatement of the decade! 
That title should probably be changed to "QuickBooks has ANOTHER problem"