OK Made those changes and tested

Same issue

Outlook crashed / Locked up and would not send the invoice.  Are you sure it is the Antivirus and not something with the pdf converter or even the connection between Quickbooks and Outlook?

I have had QB techs in my computer and they modified my Firewall to make sure anything with QB was coming in and out but this was for a different problem I was having so I am unsure it is the Antivirus.

When I get a moment to call support I will either way and IF they do find a solution I will reply to this thread again to update everyone.

But again I thought the QB engineers were actually working on this issue and were going to send out an updated release.  I have spoken with Microsoft and understand they know about the issue as well but say it is a QB known issue.