We are running on a Windows Server 2016 box.  We resolved this issue by uninstalling the current version of QBD and went back to an R3 install (happen to have downloaded the installer for R3 and found in download file).  Life is good again.  Until they fix the current version we will run on R3.  I would love to get a reach out from support when it is fixed.  I was told yesterday, after hours of phone time, we would be on an email update for the issue.  We have not received one.