QuickBooks Desktop - though it changed a few months ago to a subscription service that is hosted online. And they're not going to offer the Desktop option to new subscriptions anymore. They had said that it wouldn't be offered after July, but I think they extended it a couple of months. I haven't been following it closely since I signed up for mine. I wouldn't be surprised if they force us all to switch to Online at some point if we want to have QB at all. 

I've used QB Online as the treasurer for a small nonprofit before. There were pros and cons, but more cons for me than pros. And there's always a learning curve.