Yes, you can run payroll in QuickBooks Desktop 2024, @GC28. 

The QuickBooks Desktop Enterprise 2024 offers fully integrated payroll options to suit your business. If you're a QuickBooks Enterprise Gold or Platinum subscriber, you have QuickBooks Desktop Enhanced Payroll included in your subscription. This feature enables you to create paychecks and file taxes with ease. For QuickBooks Enterprise Diamond subscribers, QuickBooks Desktop Assisted Payroll is part of your subscription. With this feature, we take care of your tax filing and form submission, freeing up your time for other essential tasks. 

Here's an article that overviews the payroll features available in QuickBooks Enterprise, including automatic tax filing, online employee portals, and next-day direct deposit: Faster, easier payroll—all inside QuickBooks. 

To check the new features in QuickBooks Desktop 2024, check out this article: What's new in QuickBooks Desktop 2024.

You can always return to this thread for further information about processing payroll in QuickBooks Desktop. Keep safe, and have a wonderful day!