Hi @mikeshick did the Tool Hub work and if so, what option within it? Love it how QB just say use this amazing tool with a dozen options without which one to choose. I have the same issue as you and also was working fine for years until recently. I tried all the steps but none works (admin, outlook in settings, etc). In fact some of their steps are outdated - like there's no "quickbooks.exe".

I think it may be worth upgrading to QB 2023 perhaps as I don't see anyone complaining about issues with the later versions after 2021.