I've had the same problem for some time but have found a "work around" which seems to work.

Load QB (Premier Manufacturing) before I load any other program

Once QB has loaded, run a simple QB report prior to doing anything else

Close the QB report

Then proceed with loading any of the other programs I use

Since I started doing this a few months, I have not had QB abruptly & unexpectedly close on its own.

I'll leave it to the IT gurus to figure out why this simple step has worked well for me.