I'll put my best foot forward on the QuickBooks Desktop (QBDT) 22' R5 patch breaks issue to get you back on track, @sinkgordonIT.

I have other alternatives to help fix the crashing issue in your company file. Before that, have you done the troubleshooting steps provided by my colleague Jovychris_A and AbegailS above? If not yet, I'd suggest doing so.  

If you do and the problem persists, I'd recommend using the built-in browser that replaces Internet Explorer 11. It’s reliable and will include critical security updates. Internet Explorer 11 is the current browser for QBDT, but as of June 15, 2022, Microsoft will no longer support it. Read more about Microsoft’s Lifecycle Policy. To know the internal browser technical specifications, check out this link: Use our built-in browser in QuickBooks Desktop. 

Another solution is to configure the Windows Registry Editor settings manually. Before doing this, please back up your company file for future use. Once done, follow the steps below:

1. Type Regedit in your taskbar and select Registry Editor. 

        2. Add a folder called IEXPLORE.EXE in Computer\HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\App Paths\. 

        3. Click on default and set it to your path to chrome. Example: C:\Program Files\Google\Chrome\Application\chrome.exe. 

        4. Follow the on-screen instructions and restart your computer. 

I've also added some articles to QuickBooks Desktop about Internet Explorer settings and the R5 patch:

• Release notes for QuickBooks Desktop 2022
• Verify And Troubleshoot QuickBooks Desktop And Internet Explorer Settings

You may always respond here if you have any further questions about QBDT patches. I'll get back to you as soon as possible and lay down some details. Keep safe.