Same issue here with Enterprise 22 on Windows 10 and Chrome.  Chrome and Quickbooks seem to crash each other.  I've had the same frustrations with Quickbooks support and don't have the time to spend hours with them to tell me it's not their fault.  22 has been a nightmare overall.  They removed scan manager, it's crashing, the 401k reports no longer properly report the employer contribution data correctly.   I guess 22 is Intuit's ME/Vista/8... Lucky us.