After posting this, I was made aware that we actually are not using the QBWC feature in our environment. I disabled this and Intuit Data Protection on all my users machines, but QB is still crashing the same applications as before. This is becoming a serious issue, as it is crashing all Office 365 applications (alongside Chrome) and many of our accountants use Excel alongside QB. So when QB sporadically crashes Excel, they lose any unsaved work.

Now I get 10+ reports of QB crashing my user's applications each day, and having no more solutions for them is damaging the reputation my entire sysadmin team. I understand that Intuit is moving their focus toward QB Online, but the fact that this issue still doesn't have a fix / patch / workaround is terrible.