Hi @joemuscatello,

I'll handle this query for you. 

Although there isn't a direct way to set a keyboard shortcut to open QuickBooks Online (QBO), I suggest viewing the Automator app and see if there's a shortcut assigned to open QBO. You can do this by going to your Applications folder, or using the keyboard shortcut Shift + Command + A.

Preset keyboard shortcuts for QuickBooks Online are available in this article: Keyboard shortcuts for QuickBooks Online. All keyboard shortcuts are listed by category, so it's easier for you to look for a certain key combination. 

Have other questions in mind? Place them in the comments below, and I'll get back to you as soon as I can.