I have 2 desktops already with Quickbooks 2022 Pro client installed and logging into the server company files successfully, just can login only as single user without the server database manager installation. 

I have some pre-Quickbooks 2022 installations (VisualC 2015 and 2017 x86 and x64 installs, also one older VisualC 2010 from the previous Quickbooks 2019 install) that are still installed after I uninstalled Quickbooks 2022 client on the server and restarted it normally, to repair the Win2012R2 windows configuration.

I also have noticed that this Quickbooks 2022 installer does not offer to update the older 2019 installation the way previous Quickbooks installations did.  I could manually uninstall the 2019 Quickbooks installation, but I can't just restart the server in the middle of the day like I can a desktop.   It probably would require a restart to completely remove the installation.