Michelle -- I think the issue is occurring for me and others when there are multiple versions of QB installed -- which has always worked in the past. I tried re-install QB this AM, and then run the updates, but that did not seem to make a difference.

What is odd is that it does not show the QB DB manager for 2022 is even running (like it does for the other releases).

I have tried the Tools Hub and all that, and called Support -- and their "maybe" solution was to uninstall all the existing version of QB on the machine and re-install. And that just  doesn't seem like a solution to me. 

Do a search for INV-63789 and you will see there are others that have a similar issue -- but no FIX that I can find has been posted. 

I am pretty sure something is broken and Intuit needs to get their Engineering Team involved. 

This is really starting to take up a lot of time.