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Buy nowWe don't recommend running QuickBooks from a portable drive, JenniferGrace.
One of the system requirements for QuickBooks is to install it on a particular system or environment that was designed for. Hence, you need a 4X DVD-ROM drive for CD installations.
I'm adding this link for additional information: System requirements for QuickBooks Desktop 2022. It includes what operating system, hardware, software, and other requirements to run the software.
You may use a portable drive if you need to create a backup copy of your company file. Then, move the copy to a local hard drive when restoring the file.
Let me provide the steps on how restore the file.
To avoid overwriting anything, you can rename your existing company file or the backup so the names are unique. Or you can save the backup in a completely separate folder.
If you run into issues while restoring the backup file, here's how to fix them.
Keep me posted by leaving a comment below if you have additional questions about installing QuickBooks. I'll be right here to help you through the process.