Hello, brianchristenson. 

Yes, you can uninstall and install back your QuickBooks to clean all the damaged data in the system.  

However, if the same thing happens, I suggest reaching out to our customer support team, This way, one of our agents will able to pull up your account in a secure session and help you with the issue you've encountered in QuickBooks. You can refer to this article on how to reach out our support team: Contact QuickBooks Desktop support. 

Please let me know if you have any other questions. I'm always here to help. Stay safe!