I too am having the same issue. I have a saved back up profile and I have provided the back up with my login password for windows and it will not run the back up. I have the working file on a mapped drive on the server because we are multi-user. The back up does not even attempt to work and it did before. The difference I have is that I just replaced my server and I used to have 2016 and 2019 database manager on the server. Now I just have 2019 database manager and it does not even think about working. I have set the time on saved back up for a couple of minutes out to watch it and it does not do anything at all. It is beyond me how bad quickbooks deals with the file being in another location. We constantly have issues where it will not allow the file to be opened in multi-user and now this issue with the file not being able to back up. It is not that hard!!! I have tried everything to get the file to back up automatically and it will not back up.