Regardless of how you process payroll, you should be able to Efile all your employee's tax forms at once, cmadis01. 

Though, having a large volume of payroll data my trigger latency in completing the whole process. To maintain your best electronic service experience, make sure to acquire the following requirements:

• An Enhanced Payroll subscription
• A supported version of QuickBooks Desktop
• An internet connection
• The most recent payroll update

Check this out to learn more about this service: Understanding the E-File and E-Pay services.

Drop by again here if there's anything else you'd like to ask.