I just off the phone with Intuit, they say CRA issue and that Intuit is working with CRA to try and fix it. 

NO ETA. 

Also CRA has no idea what error code 500 is.  I am printing off the error message every time I try so I can fight with CRA not to penalize my clients that owe.  For the clients with refunds its not an issue as no penalty is applied.