Hi there, @bqdatabase.

I want to ensure you won't go through this error again and resolve it as quickly as possible.

Usually, this happens when QuickBooks can’t access the fiblueprint.xml file because of user permission restrictions. And when QuickBooks is used in a hosted, terminal service, or Citrix environment. To isolate the issue, you can follow the steps provided by my colleague MirriamM by making sure that you have the appropriate user permissions to C:\ProgramData and fixing the Microsoft .NET Framework, MSXML, and C++.

Moreover, you can also completely uninstall, then reinstall QuickBooks to replace your QuickBooks Desktop software and its installation files.

Here's how to remove QuickBooks:

1. Open the Windows Start menu. Search for “Control Panel”, then open Control Panel.
2. Select Programs and Features or Uninstall a Program.
3. From the list of programs, select your version of QuickBooks Desktop you want to uninstall.
4. Select Uninstall/Change and then Remove.
5. Click Next.  If you don’t see this option, sign out and sign back into Windows as an admin (or a user with admin rights).

Then, here's how to install QuickBooks Desktop.

Moreover, here's an article you can open for more tips about fixing System Exception errors.

If you have any other QuickBooks questions, please let me know by adding a comment below. I'm always here to help. Have a good one!