Thanks for asking us here in the Community, @Bagya1111. The popup will affect the Adjusted Inventory of particular Items of a Warehouse if you click the Yes option. 

However, if you opt for the No button, it will not save your changes. 

For more insights, you can check out this article to learn more about adjusting your inventory quantity or value in QuickBooks Desktop.

Feel free to come by and post some more of your concerns if you have any. I'll be right up to help you again. Take care.