Thanks for joining the thread, @lehightee.

We can only change the report information in QuickBooks Desktop, and it does not affect payroll tax calculation. We're unable to exempt the employer from the Med and SS taxes. We can exempt the employee, however, both taxes will not calculate on paychecks.

If they're not required to pay Medicare and Social Security, you can enter zero in the SS and Med field under the Company contribution part when you create a paycheck.

Feel free to browse this link on how to create a paycheck: How do I create a paycheck for an employee?

You can also check this article to set preferences for Payroll in QuickBooks Desktop: Set Preferences for Payroll.

Let me know if you have other questions about payroll. I'll be right here to help you out.