I have updated my QB 2014 with the latest update. NOW when I click on my QB file - that is on a Mac-OS Server, it now opens Mac 2014 Server, which I have never used before.  I have done the "delete pref. files" as suggested. It did not solve this issue.  If I copy the file to my desktop, and open the company file from the Qucikbooks 2014 app - it runs fine. It will not open, if the file is on my Mac OS X Server . I just updated to 10.11.3 - El Capitan.