Yes, all entries in your bank register impact the account balance.
If the transactions didn't happen, and were entered in error, then it's probably appropriate to delete or void them. However, doing this will change your financials for prior periods.
If they did happen, then they should be left in place and, if they actually did clear the bank, figure out how you reconciled. If there are inappropriate adjustments, entered because the transactions should have been reconciled but were not, then delete the adjustments and then preform a special reconciliation to mark the cleared transactions - that were not cleared before - as cleared in their place.
