I am having the same issues.  I am on QB Pro Desktop 2018.  I have no wizard despite resetting updates & downloading latest payroll this morning.  My only option under Vendors is to print/efile 1099.  When I click that it tells me to back up the company file.  I back up both via my online service via QB and do a flash drive back up version.  I restart QB & it just continues to tell me to back up & ignores I've done a back up.  What can I do?  I have restarted my company file multiple times after doing all the steps but nothing is working.