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The cost of sale or cost of goods sold is tracked if an inventory type is used for the item. Otherwise, we're unable to see the invoice profit.
We can run the Profit and Loss report to track the profitability but it will show all invoices and all purchases. Let me guide you on how to run Profit and Loss report:
I'll add this article, for more information: Run a Profit and Loss report in QuickBooks Online.
Also, you can read out this article on how to customize your financial reports: Customize your reports in QuickBooks Online.
Feel free to post again if there's anything else you need help with running a report. I'm here to help you more. All the best.