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CYBER MONDAY SALE 70% OFF QuickBooks for 3 months* Ends 12/5
Buy nowHi there, @bbmhayes.
Thank you for the update and for providing additional information.
We understand that you'd like to disable the option for customers to reply to invoices and estimates sent through QuickBooks Online. However, there is no specific option available to turn off this ability.
To work around this situation, you'll want to update your customer-facing email address to the desired email. By doing this, you can ensure that customer responses are directed to a designated email address that you've set up for communication purposes. This will help you manage customer inquiries effectively and ensure that the right person receives and responds to their messages.
Here's how:

I also encourage you to add your vote for this one by sending a feature request in the Feedback section within QuickBooks. Our product development team reviews all the feedback we receive to ensure we’re meeting the needs of our customers.
Here's how:
Additionally, you can change the email address that appears on your sales forms.
Feel free to post here in the Community if you have any concerns about sending invoices. We're always here ready to help. Have a good one!