Thank you for posting here on the Community page, bbacchus65

I'll share some clarification on how setting different pricing for different customers will work with Quickbooks Desktop Enterprise.

This works when using price rules which allows you to create a more precise condition on when the price of an item changes when you sell it to different customers. With this, you can use the Advanced Pricing feature so QuickBooks automatically changes the prices of items on sales forms according to the rules you create.

Here's how to enable this feature:

1. Select Preferences from the QuickBooks Edit menu.
2. Click Sales & Customers from the left pane, then click the Company Preferences tab.
3. Select Enable Advanced Pricing from the Custom Pricing section.
4. Choose how you want to handle price rounding.
5. Click OK.

Moreover, let me also attach this link to help you manage price rules in QuickBooks: Use Advanced Pricing.

If you have anything else I can help you with regarding pricing in QBDT, please don't hesitate to post them here. I'll be glad to help.