I hope you enjoyed your holiday, Kymstone. I'll help you process the pay run.
I've checked our file and didn't see any reported cases same as yours. This is probably a cache issue.
Let's isolate this. To start with, open QuickBooks Online using an incognito window. From there, try to run your payroll. If you're able to do so, go back to your main browser, then clear the cache. We recommend clearing them every now and them. This helps to prevent the system to act differently.
On the other hand, using a different browser can fix issues like this (Google Chrome, Mozilla Firefox, or Internet Explorer).
You can keep us updated after trying these steps. We're just right here to help you.